Enzyme

Enzyme is a tool for compiling large knowledge bases—such as markdown files, Obsidian vaults, and Readwise exports—into a semantically-rich concept graph in under 20 seconds. It surfaces connections and recurring themes across your documents as pre-computed questions or 'catalysts,' enabling AI agents to rapidly query and retrieve insight, even across unrelated content. Designed for developers, researchers, and anyone managing complex knowledge stores, Enzyme operates locally for fast, private searching and offers both CLI and MCP server integration.